Excess of sirtuins can produce anxiety, a possible evolutionary adaptation to dietary restriction.
CAMBRIDGE, Mass.–(ENEWSPF)–December 9, 2011. Over the past decade, MIT biologist Leonard Guarente and others have shown that very-low-calorie diets provoke a comprehensive physiological response that promotes survival, all orchestrated by a set of proteins called sirtuins.
In a new paperthat appeared online in Cell on Dec. 8, Guarente and colleagues have now shown that sirtuins likely also play a key role…






