ROCHESTER, Minn.–(ENEWSPF)–February 11, 2014. Mayo Clinic researchers have shed light on a new mechanism by which prostate cancerdevelops in men. Central to development of nearly all prostate cancer cases are malfunctions in the androgen receptor — the cellular component that binds to male hormones. The research team has shown that SPOP, a protein that is most frequently mutated in human prostate cancers, is a key regulator of androgen receptor activity that prevents uncontrolled growth…






