Health and Fitness

Newly Identified Molecular Mechanism Plays Role in Obesity-related Type 2 Diabetes Development

Depiction of nitrosylated IRE1 on the ER membrane.  The red-blue molecules are NO;   yellow represents the nitrosylated cysteines of IRE1.
Depiction of nitrosylated IRE1 on the ER membrane. The red-blue molecules are NO; yellow represents the nitrosylated cysteines of IRE1.

Boston, MA ─(ENEWSPF)–July 31, 2015.  New research from Harvard T.H. Chan School of Public Health describes a molecular mechanism that helps explain how obesity-related inflammation can lead to type 2 diabetes. The findings describe a surprising connection between two molecular processes that are known to be involved in the development of metabolic disease—inflammation and…

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