Washington, DC–(ENEWSPF)–December 6, 2013. In a new study exploring gene-environment interactions, researchers find that individuals with a genetic mutation linked to Parkinson’s disease are more likely to develop the neurodegenerative disease if they are exposed to pesticides. The study, Isogenic Human iPSC Parkinson’s Model Shows Nitrosative Stress-Induced Dysfunction in MEF 2-PGC1α Transcription, identifies the molecule that protects neurons from pesticides, ties genetic mutation to pesticide exposure, and demonstrates that low dose exposure can cause Parkinson’s disease.
